Frequently Asked Questions
Psilocybin is a naturally occurring psychedelic compound found in certain species of mushrooms. When consumed, the body converts psilocybin into psilocin, which interacts with serotonin receptors in the brain. This can lead to altered states of consciousness, enhanced introspection, emotional processing, and, for some, profound spiritual experiences. Psilocybin has been used for centuries in various cultures for healing and personal growth.
Psilocybin is considered to have a low toxicity profile and is generally safe when used in a controlled environment with proper preparation and guidance. Research suggests that psilocybin is non-addictive and has a low risk of physical harm compared to many other substances. However, individual experiences can vary, and proper screening is essential to ensure safety.
No, psilocybin is not physically addictive and does not lead to compulsive use. In fact, studies suggest it may help reduce addiction to substances like alcohol and nicotine by promoting deep personal insight and behavioral change.
Psilocybin primarily affects the brain by interacting with serotonin receptors, particularly the 5-HT2A receptor. This leads to increased neuroplasticity, changes in brain network activity, and a temporary shift in perception and cognition. Below are some ways that psilocybin works to make change for an individual.
Rewires brain connectivity – Psilocybin decreases rigid patterns of thinking by disrupting the default mode network (DMN), which is often overactive in individuals with depression, PTSD and anxiety.
Increases emotional openness – Many users report a greater ability to process emotions, helping to resolve stuck patterns of sadness or fear.
Reduces negative self-talk – By quieting repetitive negative thought loops, psilocybin can help break cycles of rumination and self-criticism.
Promotes emotional release – Psilocybin can help individuals revisit traumatic memories in a less fearful, more objective way, allowing for deeper healing.
Enhances neural flexibility – Trauma often "locks" the brain into rigid fear-based responses. Psilocybin loosens these pathways, enabling new perspectives on past events.
Increases connection and safety – Many report a sense of oneness and self-compassion, which can counteract the isolation often caused by trauma.
Enhances motivation for change – Users often experience profound insights about their behaviors, leading to increased willpower to change.​
The number of psilocybin sessions needed varies based on individual goals, personal history, and the depth of healing or insight desired. Some people experience significant benefits from a single session, while others choose to do multiple sessions to deepen their healing process. The ideal number of sessions depends on:
Your goals – Are you seeking clarity, emotional healing, or long-term personal growth?
The depth of the issues being addressed – Often those who struggle with chronic conditions or trauma see best results with several sessions spaced out over months or even years.
How well your experience is integrated – Some people find that one session with proper integration is enough, while others prefer continued support through additional journeys.
Research suggests that psilocybin-assisted therapy may help with a variety of difficulties, including:
Depression
Anxiety
Obssessive-Compulsive Disorder
PTSD
Addiction (alcohol, nicotine, and other substances)
End-of-life distress
Trauma and grief
Existential or spiritual crises
Psilocybin is not a cure, but many individuals find that it can help them process emotions, reframe negative thought patterns, and gain insights that contribute to long-term healing.
Psilocybin therapy may be beneficial if you are seeking deep personal healing, struggling with mental health challenges, or feeling stuck in life. However, it is not for everyone. People with a history of schizophrenia, psychosis, or certain heart conditions may not be suitable candidates. A consultation with a licensed facilitator can help determine if psilocybin therapy aligns with your needs and goals.
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A psilocybin-assisted session typically includes:
Preparation – Before your session, you will have a consultation to discuss your intentions, medical history, and any concerns. You will then participate in a formal preparation session. Your facilitator will help you prepare mentally and emotionally for the experience.
The Session – On the day of the session, you will come to our office and get settled into your therapy room. You'll review your intentions with your licensed facilitator and process any feelings you are having. After consuming psilocybin, you will be supported through the experience, which may include deep introspection, emotional release, and altered perception.
Integration – After the session, you will meet with your facilitator to process and integrate your experience. This helps translate insights into meaningful, lasting change in your life.
Yes, psilocybin-assisted therapy is legal in Colorado under the Natural Medicine Health Act (Proposition 122/SB290). Within the regulated model, psilocybin is used in licensed healing centers with trained facilitators. Personal use is also legal in Colorado, but commercial sales of psilocybin remain illegal. You can find the senate bill here. Reset, LLC operates fully within state regulations to ensure safe and legal access to psilocybin-assisted therapy.
A natural medicine healing center is a licensed facility where individuals can legally access and experience natural medicines (currently only psilocybin) under the guidance of trained facilitators. Trained facilitators can be clinical or non-clinical. These centers provide safe, structured environments designed to support healing, personal growth, and well-being. In Colorado, natural medicine healing centers operate under strict state regulations to ensure safety and efficacy.
Licensed Facilitator (NMF): Can provide psilocybin facilitation but does not need a healthcare license. They must complete state-approved training and meet experience requirements.
Licensed Clinical Facilitator (NMCF): Must hold an active license in a healthcare profession and meet additional education and consultation requirements. They have a broader scope of practice, including working with individuals with complex mental health needs.​
Facilitator in Training (NMIT): These providers have completed all necessary education to be either a licensed facilitator or licensed clinical facilitator. They still have yet to complete parts or all of the other requirements including a practicum experience and consultation. During their in training period they are allowed to practice natural medicine services independently.
All licensed facilitators and clinical facilitators in Colorado must be registered with the state’s regulatory body. You can verify a facilitator’s license by checking the Colorado Department of Regulatory Agencies (DORA) Natural Medicine Program website.
To look up a licensed facilitator:
Visit the Colorado DORA License Lookup website.
Choose "Natural Medicine" from the drop down menu.
Enter the facilitator’s name or license number.
Confirm that their license is active and in good standing.
At Reset, LLC, we only work with licensed clinical facilitators while ensuring compliance with Colorado state regulations.
Licensed natural medicine healing centers must be registered with the state and adhere to strict safety and compliance regulations. To verify if a healing center is legally licensed:
Visit Colorado's Natural Medicine Division website.
Select "Licensee Look-Up Tool" from the menu on the right side of the page.
Click to "search for a Facility instead of a person".
Under License Type choose the category for NM Healing Centers.
Search by the business name or license number or simply click "search" for all licensees that are pending.
Confirm that the healing center is active and compliant with state laws.​
Our pricing varies based on the facilitator and the specific services requested. Please note that the cost of operating in this field is substantial and expected to continue rising in the coming years. A single round of services typically involves 10–12 hours of direct client care by our clinicians which is roughly equivalent to three months of traditional talk therapy. That said, we are committed to making these services as accessible as possible. Please reach out to discuss pricing options and explore what might work for you.
Unfortunately, psilocybin-assisted therapy is not currently a covered service under major health insurances. Therefore, the psilocybin-assisted services-which include a preparatory session, psilocybin session and integration session-must be paid for out of pocket. If you would like to have additional talk therapy, preparatory or integration sessions we may be able to utilize your insurance. Contact us for more details!
